Current projects

Viruses are complex machines that can be found in many different niches where cells are. In fact, they can also be found in extreme environments such as hot springs or salty lakes. HCIV-1 is an archaeal halophilic virus that can thrive in a wide concentration of salts, ranging from millimolar up to 5M. Cryo-EM structure of HCIV-1 and genetic...

Cellular organisms from all three domains of life, from the simple prokaryotes to highly-organized multicellular eukaryotes, are infected with viruses that have coevolved with their hosts for millions of years. As a result of this perennial arms race, viruses are efficient nanomachines that have adapted to function in any environment where their...

Effective airborne transmission of coronaviruses via liquid microdroplets requires a virion structure that must withstand harsh environmental conditions [1]. Due to the demanding biosafety requirements for study of human respiratory viruses, it is important to develop surrogate models to facilitate their investigation. Here we explore the...